Mouse Hfe activation kit by CRISPRa

CAT#: GA201883

Hfe CRISPRa kit - CRISPR gene activation of mouse homeostatic iron regulator

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Hfe
• Locus ID: 15216
• Kit Components:

  GA201883G1, Hfe gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA201883G2, Hfe gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA201883G3, Hfe gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001347493, NM_010424
• UniProt ID: P70387
• Synonyms: MR2
• Summary: Binds to transferrin receptor (TFR) and reduces its affinity for iron-loaded transferrin.[UniProtKB/Swiss-Prot Function]