Mouse Bckdk activation kit by CRISPRa

CAT#: GA200380

Bckdk CRISPRa kit - CRISPR gene activation of mouse branched chain ketoacid dehydrogenase kinase

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Bckdk
• Locus ID: 12041
• Kit Components:

  GA200380G1, Bckdk gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA200380G2, Bckdk gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA200380G3, Bckdk gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_009739
• UniProt ID: O55028
• Synonyms: AI327402
• Summary: Catalyzes the phosphorylation and inactivation of the branched-chain alpha-ketoacid dehydrogenase complex, the key regulatory enzyme of the valine, leucine and isoleucine catabolic pathways. Key enzyme that regulate the activity state of the BCKD complex.[UniProtKB/Swiss-Prot Function]