Human SAMD9L activation kit by CRISPRa

CAT#: GA116471

SAMD9L CRISPRa kit - CRISPR gene activation of human sterile alpha motif domain containing 9 like

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: SAMD9L
• Locus ID: 219285
• Kit Components:

  GA116471G1, SAMD9L gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA116471G2, SAMD9L gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA116471G3, SAMD9L gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001303496, NM_001303497, NM_001303498, NM_001303500, NM_152703, NM_001350082, NM_001350083, NM_001350084, NM_001350085
• UniProt ID: Q8IVG5
• Synonyms: ATXPC; C7orf6; DRIF2; UEF1
• Summary: This gene encodes a cytoplasmic protein that acts as a tumor suppressor but also plays a key role in cell proliferation and the innate immune response to viral infection. The encoded protein contains an N-terminal sterile alpha motif domain. Naturally occurring mutations in this gene are associated with myeloid disorders such as juvenile myelomonocytic leukemia, acute myeloid leukemia, and myelodysplastic syndrome. Naturally occurring mutations are also associated with hepatitis-B related hepatocellular carcinoma, normophosphatemic familial tumoral calcinosis, and ataxia-pancytopenia syndrome. [provided by RefSeq, Apr 2017]