Human DNAH12 activation kit by CRISPRa

CAT#: GA116400

DNAH12 CRISPRa kit - CRISPR gene activation of human dynein axonemal heavy chain 12

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: DNAH12
• Locus ID: 201625
• Kit Components:

  GA116400G1, DNAH12 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA116400G2, DNAH12 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA116400G3, DNAH12 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001291661, NM_178504, NM_198564, NM_001366028
• UniProt ID: Q6ZR08
• Synonyms: DHC3; DLP12; DNAH7L; DNAH12L; DNAHC3; DNAHC12; DNHD2; HDHC3; HL-19; HL19
• Summary: Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly (By similarity).[UniProtKB/Swiss-Prot Function]