Human ZNRF4 activation kit by CRISPRa

CAT#: GA115650

ZNRF4 CRISPRa kit - CRISPR gene activation of human zinc and ring finger 4

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: ZNRF4
• Locus ID: 148066
• Kit Components:

  GA115650G1, ZNRF4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA115650G2, ZNRF4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA115650G3, ZNRF4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_181710
• UniProt ID: Q8WWF5
• Synonyms: RNF204; SPERIZIN; spzn; Ssrzf1
• Summary: E3 ubiquitin-protein ligase which specifically induces ubiquitination and proteasomal degradation of CANX within the endoplasmic reticulum (PubMed:21205830). Could have a role in spermatogenesis (By similarity).[UniProtKB/Swiss-Prot Function]