Human CPEB2 activation kit by CRISPRa

CAT#: GA115185

CPEB2 CRISPRa kit - CRISPR gene activation of human cytoplasmic polyadenylation element binding protein 2

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: CPEB2
• Locus ID: 132864
• Kit Components:

  GA115185G1, CPEB2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA115185G2, CPEB2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA115185G3, CPEB2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001177381, NM_001177382, NM_001177383, NM_001177384, NM_182485, NM_182646
• UniProt ID: Q7Z5Q1
• Synonyms: CPE-BP2; CPEB-2; hCPEB-2
• Summary: The protein encoded by this gene is highly similar to cytoplasmic polyadenylation element binding protein (CPEB), an mRNA-binding protein that regulates cytoplasmic polyadenylation of mRNA as a trans factor in oogenesis and spermatogenesis. Studies of the similar gene in mice suggested a possible role of this protein in transcriptionally inactive haploid spermatids. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]