Human NALP5 (NLRP5) activation kit by CRISPRa

CAT#: GA114923

NLRP5 CRISPRa kit - CRISPR gene activation of human NLR family pyrin domain containing 5

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: NLRP5
• Locus ID: 126206
• Kit Components:

  GA114923G1, NALP5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA114923G2, NALP5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA114923G3, NALP5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_153447
• UniProt ID: P59047
• Synonyms: CLR19.8; MATER; NALP5; PAN11; PYPAF8
• Summary: The protein encoded by this gene belongs to the NALP protein family. Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). Expression of this gene is restricted to the oocyte. A mouse gene that encodes a maternal oocyte protein, similar to this encoded protein, is required for normal early embryogenesis. [provided by RefSeq, Jul 2008]