Human TUBA3E activation kit by CRISPRa

CAT#: GA114363

TUBA3E CRISPRa kit - CRISPR gene activation of human tubulin alpha 3e

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: TUBA3E
• Locus ID: 112714
• Kit Components:

  GA114363G1, TUBA3E gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA114363G2, TUBA3E gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA114363G3, TUBA3E gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_207312
• UniProt ID: Q6PEY2
• Synonyms: tubulin, alpha 3e
• Summary: Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulin. The genes encoding these microtubule constituents are part of the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. This gene encodes an alpha tubulin that highly conserved among species. A missense mutation in this gene has been potentially linked to microlissencephaly and global developmental delay. [provided by RefSeq, Jul 2016]