Human SPECC1 activation kit by CRISPRa

CAT#: GA114219

SPECC1 CRISPRa kit - CRISPR gene activation of human sperm antigen with calponin homology and coiled-coil domains 1

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: SPECC1
• Locus ID: 92521
• Kit Components:

  GA114219G1, SPECC1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA114219G2, SPECC1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA114219G3, SPECC1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001033553, NM_001033554, NM_001033555, NM_001243438, NM_001243439, NM_152904
• UniProt ID: Q5M775
• Synonyms: CYTSB; HCMOGT-1; HCMOGT1; NSP
• Summary: The protein encoded by this gene belongs to the cytospin-A family. It is localized in the nucleus, and highly expressed in testis and some cancer cell lines. A chromosomal translocation involving this gene and platelet-derived growth factor receptor, beta gene (PDGFRB) may be a cause of juvenile myelomonocytic leukemia. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]