Human C9orf123 (TMEM261) activation kit by CRISPRa

CAT#: GA114070

DMAC1 CRISPRa kit - CRISPR gene activation of human distal membrane arm assembly complex 1

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: DMAC1
• Locus ID: 90871
• Kit Components:

  GA114070G1, C9orf123 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA114070G2, C9orf123 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA114070G3, C9orf123 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001318058, NM_001318059, NM_033428
• UniProt ID: Q96GE9
• Synonyms: C9orf123
• Summary: Required for the assembly of the mitochondrial NADH:ubiquinone oxidoreductase complex (complex I). Involved in the assembly of the distal region of complex I.[UniProtKB/Swiss-Prot Function]