Human Naked1 (NKD1) activation kit by CRISPRa

CAT#: GA113872

NKD1 CRISPRa kit - CRISPR gene activation of human NKD inhibitor of WNT signaling pathway 1

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: NKD1
• Locus ID: 85407
• Kit Components:

  GA113872G1, Naked1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA113872G2, Naked1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA113872G3, Naked1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_033119
• UniProt ID: Q969G9
• Synonyms: Naked1
• Summary: In the mouse, Nkd is a Dishevelled (see DVL1; MIM 601365)-binding protein that functions as a negative regulator of the Wnt (see WNT1; MIM 164820)-beta-catenin (see MIM 116806)-Tcf (see MIM 602272) signaling pathway.[supplied by OMIM, Jun 2003]