Human USP46 activation kit by CRISPRa

CAT#: GA112177

USP46 CRISPRa kit - CRISPR gene activation of human ubiquitin specific peptidase 46

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: USP46
• Locus ID: 64854
• Kit Components:

  GA112177G1, USP46 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA112177G2, USP46 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA112177G3, USP46 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001134223, NM_001286767, NM_001286768, NM_022832
• UniProt ID: P62068
• Synonyms: FLJ11850; FLJ12552; FLJ14283; FLJ39393
• Summary: Modification of cellular proteins by ubiquitin is an essential regulatory mechanism controlled by the coordinated action of multiple ubiquitin-conjugating and deubiquitinating enzymes. USP46 belongs to a large family of cysteine proteases that function as deubiquitinating enzymes (Quesada et al., 2004 [PubMed 14715245]).[supplied by OMIM, Jun 2009]