Human XAF1 activation kit by CRISPRa

CAT#: GA110236

XAF1 CRISPRa kit - CRISPR gene activation of human XIAP associated factor 1

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: XAF1
• Locus ID: 54739
• Kit Components:

  GA110236G1, XAF1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA110236G2, XAF1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA110236G3, XAF1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_017523, NM_199139, NR_046396, NR_046397, NR_046398, NM_001353134, NM_001353135, NM_001353136, NM_001353137, NM_001353138, NM_001353139, NM_001353140
• UniProt ID: Q6GPH4
• Synonyms: BIRC4BP; HSXIAPAF1; XIAPAF1
• Summary: This gene encodes a protein which binds to and counteracts the inhibitory effect of a member of the IAP (inhibitor of apoptosis) protein family. IAP proteins bind to and inhibit caspases which are activated during apoptosis. The proportion of IAPs and proteins which interfere with their activity, such as the encoded protein, affect the progress of the apoptosis signaling pathway. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]