Human Cytokeratin 20 (KRT20) activation kit by CRISPRa

CAT#: GA110124

KRT20 CRISPRa kit - CRISPR gene activation of human keratin 20

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: KRT20
• Locus ID: 54474
• Kit Components:

  GA110124G1, Cytokeratin 20 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA110124G2, Cytokeratin 20 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA110124G3, Cytokeratin 20 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_019010
• UniProt ID: P35900
• Synonyms: CD20; CK-20; CK20; K20; KRT21
• Summary: The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This cytokeratin is a major cellular protein of mature enterocytes and goblet cells and is specifically expressed in the gastric and intestinal mucosa. The type I cytokeratin genes are clustered in a region of chromosome 17q12-q21. [provided by RefSeq, Jul 2008]