Human ARHGEF4 activation kit by CRISPRa

CAT#: GA109440

ARHGEF4 CRISPRa kit - CRISPR gene activation of human Rho guanine nucleotide exchange factor 4

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: ARHGEF4
• Locus ID: 50649
• Kit Components:

  GA109440G1, ARHGEF4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA109440G2, ARHGEF4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA109440G3, ARHGEF4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_015320, NM_032995, NM_001367493
• UniProt ID: Q9NR80
• Synonyms: ASEF; ASEF1; GEF4; STM6
• Summary: Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The protein encoded by this gene may form complex with G proteins and stimulate Rho-dependent signals. Multiple alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jun 2013]