Human OR8G1 activation kit by CRISPRa

CAT#: GA108871

OR8G1 CRISPRa kit - CRISPR gene activation of human olfactory receptor family 8 subfamily G member 1 (gene/pseudogene)

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: OR8G1
• Locus ID: 26494
• Kit Components:

  GA108871G1, OR8G1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA108871G2, OR8G1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA108871G3, OR8G1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001002905, NM_012379, NR_045681
• UniProt ID: Q15617
• Synonyms: HSTPCR25; OR8G1P; TPCR25
• Summary: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. This family member represents a polymorphic pseudogene, whereby some individuals have a functional allele that encodes a full-length protein, while others have a non-functional allele due to the presence of an early stop codon and a 3' end deletion. [provided by RefSeq, Feb 2014]