Human Fascin 2 (FSCN2) activation kit by CRISPRa

CAT#: GA108540

FSCN2 CRISPRa kit - CRISPR gene activation of human fascin actin-bundling protein 2, retinal

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: FSCN2
• Locus ID: 25794
• Kit Components:

  GA108540G1, Fascin 2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA108540G2, Fascin 2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA108540G3, Fascin 2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001077182, NM_012418
• UniProt ID: O14926
• Synonyms: RFSN; RP30
• Summary: This gene encodes a member of the fascin protein family. Fascins crosslink actin into filamentous bundles within dynamic cell extensions. This family member is proposed to play a role in photoreceptor disk morphogenesis. A mutation in this gene results in one form of autosomal dominant retinitis pigmentosa and macular degeneration. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]