Human ARHGEF14 (MCF2L) activation kit by CRISPRa

CAT#: GA108173

MCF2L CRISPRa kit - CRISPR gene activation of human MCF.2 cell line derived transforming sequence like

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: MCF2L
• Locus ID: 23263
• Kit Components:

  GA108173G1, ARHGEF14 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA108173G2, ARHGEF14 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA108173G3, ARHGEF14 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001112732, NM_001320815, NM_001320816, NM_001320817, NM_024979, NM_001366644, NM_001366645, NM_001366646
• UniProt ID: O15068
• Synonyms: ARHGEF14; DBS; OST
• Summary: This gene encodes a guanine nucleotide exchange factor that interacts specifically with the GTP-bound Rac1 and plays a role in the Rho/Rac signaling pathways. A variant in this gene was associated with osteoarthritis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]