Human ASC 2 (NCOA6) activation kit by CRISPRa

CAT#: GA108003

NCOA6 CRISPRa kit - CRISPR gene activation of human nuclear receptor coactivator 6

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: NCOA6
• Locus ID: 23054
• Kit Components:

  GA108003G1, ASC 2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA108003G2, ASC 2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA108003G3, ASC 2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001242539, NM_001318240, NM_014071
• UniProt ID: Q14686
• Synonyms: AIB3; ASC2; NRC; PRIP; RAP250; TRBP
• Summary: The protein encoded by this gene is a transcriptional coactivator that can interact with nuclear hormone receptors to enhance their transcriptional activator functions. This protein has been shown to be involved in the hormone-dependent coactivation of several receptors, including prostanoid, retinoid, vitamin D3, thyroid hormone, and steroid receptors. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jun 2011]