Human EB2 (MAPRE2) activation kit by CRISPRa

CAT#: GA107540

MAPRE2 CRISPRa kit - CRISPR gene activation of human microtubule associated protein RP/EB family member 2

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: MAPRE2
• Locus ID: 10982
• Kit Components:

  GA107540G1, EB2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA107540G2, EB2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA107540G3, EB2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001143826, NM_001143827, NM_001256420, NM_014268, NR_026570, NR_046177
• UniProt ID: Q15555
• Synonyms: EB1; EB2; RP1
• Summary: The protein encoded by this gene shares significant homology to the adenomatous polyposis coli (APC) protein-binding EB1 gene family. This protein is a microtubule-associated protein that is necessary for spindle symmetry during mitosis. It is thought to play a role in the tumorigenesis of colorectal cancers and the proliferative control of normal cells. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2012]