Human BAG5 activation kit by CRISPRa

CAT#: GA106374

BAG5 CRISPRa kit - CRISPR gene activation of human BCL2 associated athanogene 5

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: BAG5
• Locus ID: 9529
• Kit Components:

  GA106374G1, BAG5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA106374G2, BAG5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA106374G3, BAG5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001015048, NM_001015049, NM_004873
• UniProt ID: Q9UL15
• Synonyms: BAG-5
• Summary: The protein encoded by this gene is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]