Human SARA (ZFYVE9) activation kit by CRISPRa

CAT#: GA106252

ZFYVE9 CRISPRa kit - CRISPR gene activation of human zinc finger FYVE-type containing 9

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: ZFYVE9
• Locus ID: 9372
• Kit Components:

  GA106252G1, SARA gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA106252G2, SARA gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA106252G3, SARA gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_004799, NM_007323, NM_007324
• UniProt ID: O95405
• Synonyms: MADHIP; NSP; PPP1R173; SARA; SMADIP
• Summary: This gene encodes a double zinc finger motif-containing protein that participates in the transforming growth factor-beta (TGFB) signalling pathway. The encoded protein interacts directly with SMAD2 and SMAD3, and recruits SMAD2 to the TGFB receptor. There are multiple pseudogenes for this gene on chromosomes 2, 15, and X. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013]