Human CCPG1 activation kit by CRISPRa

CAT#: GA106159

CCPG1 CRISPRa kit - CRISPR gene activation of human cell cycle progression 1

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: CCPG1
• Locus ID: 9236
• Kit Components:

  GA106159G1, CCPG1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA106159G2, CCPG1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA106159G3, CCPG1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001204450, NM_001204451, NM_004748, NM_020739
• UniProt ID: Q9ULG6
• Synonyms: CPR8
• Summary: Acts as an assembly platform for Rho protein signaling complexes. Limits guanine nucleotide exchange activity of MCF2L toward RHOA, which results in an inhibition of both its transcriptional activation ability and its transforming activity. Does not inhibit activity of MCF2L toward CDC42, or activity of MCF2 toward either RHOA or CDC42 (By similarity). May be involved in cell cycle regulation.[UniProtKB/Swiss-Prot Function]