Human PDLIM1 activation kit by CRISPRa

CAT#: GA106077

PDLIM1 CRISPRa kit - CRISPR gene activation of human PDZ and LIM domain 1

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: PDLIM1
• Locus ID: 9124
• Kit Components:

  GA106077G1, PDLIM1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA106077G2, PDLIM1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA106077G3, PDLIM1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_020992
• UniProt ID: O00151
• Synonyms: CLIM1; CLP-36; CLP36; hCLIM1; HEL-S-112
• Summary: This gene encodes a member of the enigma protein family. The protein contains two protein interacting domains, a PDZ domain at the amino terminal end and one to three LIM domains at the carboxyl terminal. It is a cytoplasmic protein associated with the cytoskeleton. The protein may function as an adapter to bring other LIM-interacting proteins to the cytoskeleton. Pseudogenes associated with this gene are located on chromosomes 3, 14 and 17. [provided by RefSeq, Oct 2012]