Human TXN activation kit by CRISPRa

CAT#: GA105025

TXN CRISPRa kit - CRISPR gene activation of human thioredoxin

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: TXN
• Locus ID: 7295
• Kit Components:

  GA105025G1, TXN gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA105025G2, TXN gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA105025G3, TXN gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001244938, NM_003329
• UniProt ID: P10599
• Synonyms: TRDX; TRX; TRX1
• Summary: The protein encoded by this gene acts as a homodimer and is involved in many redox reactions. The encoded protein is active in the reversible S-nitrosylation of cysteines in certain proteins, which is part of the response to intracellular nitric oxide. This protein is found in the cytoplasm. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]