Human RFX3 activation kit by CRISPRa

CAT#: GA104085

RFX3 CRISPRa kit - CRISPR gene activation of human regulatory factor X3

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: RFX3
• Locus ID: 5991
• Kit Components:

  GA104085G1, RFX3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104085G2, RFX3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104085G3, RFX3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001282116, NM_001282117, NM_002919, NM_134428
• UniProt ID: P48380
• Summary: This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X2, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with other RFX family members. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2013]