Human PDE6H activation kit by CRISPRa

CAT#: GA103446

PDE6H CRISPRa kit - CRISPR gene activation of human phosphodiesterase 6H

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: PDE6H
• Locus ID: 5149
• Kit Components:

  GA103446G1, PDE6H gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103446G2, PDE6H gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103446G3, PDE6H gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_006205
• UniProt ID: Q13956
• Synonyms: ACHM6; RCD3
• Summary: This gene encodes the inhibitory (or gamma) subunit of the cone-specific cGMP phosphodiesterase, which is a tetramer composed of two catalytic chains (alpha and beta), and two inhibitory chains (gamma). It is specifically expressed in the retina, and is involved in the transmission and amplification of the visual signal. Mutations in this gene are associated with retinal cone dystrophy type 3A (RCD3A). [provided by RefSeq, Mar 2010]