Human MYO1D activation kit by CRISPRa

CAT#: GA103081

MYO1D CRISPRa kit - CRISPR gene activation of human myosin ID

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: MYO1D
• Locus ID: 4642
• Kit Components:

  GA103081G1, MYO1D gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103081G2, MYO1D gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103081G3, MYO1D gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001303279, NM_001303280, NM_015194
• UniProt ID: O94832
• Synonyms: myr4; PPP1R108
• Summary: Unconventional myosin that functions as actin-based motor protein with ATPase activity (By similarity). Plays a role in endosomal protein trafficking, and especially in the transfer of cargo proteins from early to recycling endosomes (By similarity). Required for normal planar cell polarity in ciliated tracheal cells, for normal rotational polarity of cilia, and for coordinated, unidirectional ciliary movement in the trachea. Required for normal, polarized cilia organization in brain ependymal epithelial cells (By similarity).[UniProtKB/Swiss-Prot Function]