Human MEST activation kit by CRISPRa

CAT#: GA102882

MEST CRISPRa kit - CRISPR gene activation of human mesoderm specific transcript

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: MEST
• Locus ID: 4232
• Kit Components:

  GA102882G1, MEST gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102882G2, MEST gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102882G3, MEST gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001253900, NM_001253901, NM_001253902, NM_002402, NM_177524, NM_177525
• UniProt ID: Q5EB52
• Synonyms: PEG1
• Summary: This gene encodes a member of the alpha/beta hydrolase superfamily. It is imprinted, exhibiting preferential expression from the paternal allele in fetal tissues, and isoform-specific imprinting in lymphocytes. The loss of imprinting of this gene has been linked to certain types of cancer and may be due to promotor switching. The encoded protein may play a role in development. Alternatively spliced transcript variants encoding multiple isoforms have been identified for this gene. Pseudogenes of this gene are located on the short arm of chromosomes 3 and 4, and the long arm of chromosomes 6 and 15. [provided by RefSeq, Dec 2011]