Human GPIP137 (CAPRIN1) activation kit by CRISPRa

CAT#: GA102768

CAPRIN1 CRISPRa kit - CRISPR gene activation of human cell cycle associated protein 1

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: CAPRIN1
• Locus ID: 4076
• Kit Components:

  GA102768G1, GPIP137 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102768G2, GPIP137 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102768G3, GPIP137 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_005898, NM_203364
• UniProt ID: Q14444
• Synonyms: GPIAP1; GPIP137; GRIP137; M11S1; p137GPI; RNG105
• Summary: May regulate the transport and translation of mRNAs of proteins involved in synaptic plasticity in neurons and cell proliferation and migration in multiple cell types. Binds directly and selectively to MYC and CCND2 RNAs. In neuronal cells, directly binds to several mRNAs associated with RNA granules, including BDNF, CAMK2A, CREB1, MAP2, NTRK2 mRNAs, as well as to GRIN1 and KPNB1 mRNAs, but not to rRNAs.[UniProtKB/Swiss-Prot Function]