Human Lactoferrin (LTF) activation kit by CRISPRa

CAT#: GA102751

LTF CRISPRa kit - CRISPR gene activation of human lactotransferrin

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: LTF
• Locus ID: 4057
• Kit Components:

  GA102751G1, Lactoferrin gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102751G2, Lactoferrin gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102751G3, Lactoferrin gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001199149, NM_001321121, NM_001321122, NM_002343
• UniProt ID: P02788
• Synonyms: GIG12; HEL110; HLF2; LF
• Summary: This gene is a member of the transferrin family of genes and its protein product is found in the secondary granules of neutrophils. The protein is a major iron-binding protein in milk and body secretions with an antimicrobial activity, making it an important component of the non-specific immune system. The protein demonstrates a broad spectrum of properties, including regulation of iron homeostasis, host defense against a broad range of microbial infections, anti-inflammatory activity, regulation of cellular growth and differentiation and protection against cancer development and metastasis. Antimicrobial, antiviral, antifungal and antiparasitic activity has been found for this protein and its peptides. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2014]