AMPD1 (NM_001172626) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC230489L3V
- LentiORF®
Lenti ORF particles, AMPD1 (Myc-DDK-tagged)-Human adenosine monophosphate deaminase 1 (AMPD1), transcript variant 2, 200ul, >10^7 TU/mL
Lentiviral Particles: mGFP w/ Puro
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Specifications
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
Tag | Myc-DDK |
Symbol | AMPD1 |
Synonyms | MAD; MADA; MMDD |
Mammalian Cell Selection | Puromycin |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_001172626 |
ORF Size | 2328 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC230489).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_001172626.1, NP_001166097.1 |
RefSeq ORF | 2232 bp |
Locus ID | 270 |
UniProt ID | P23109 |
Cytogenetics | 1p13.2 |
Protein Families | Druggable Genome |
Protein Pathways | Metabolic pathways, Purine metabolism |
MW | 90.2 kDa |
Gene Summary | Adenosine monophosphate deaminase 1 catalyzes the deamination of AMP to IMP in skeletal muscle and plays an important role in the purine nucleotide cycle. Two other genes have been identified, AMPD2 and AMPD3, for the liver- and erythocyte-specific isoforms, respectively. Deficiency of the muscle-specific enzyme is apparently a common cause of exercise-induced myopathy and probably the most common cause of metabolic myopathy in the human. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.[provided by RefSeq, Feb 2010] |
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