VMAT1 (SLC18A1) (NM_001142325) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC227957L1V

Lenti ORF particles, SLC18A1 (Myc-DDK tagged) - Human solute carrier family 18 (vesicular monoamine), member 1 (SLC18A1), transcript variant 4, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: VMAT1
• Synonyms: CGAT; VAT1; VMAT1
• Mammalian Cell Selection: None
• Vector: pLenti-C-Myc-DDK
• ACCN: NM_001142325
• ORF Size: 1416 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC227957).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001142325.1, NP_001135797.1
• RefSeq ORF: 1419 bp
• Locus ID: 6570
• UniProt ID: P54219
• Cytogenetics: 8p21.3
• Protein Families: Transmembrane
• Protein Pathways: Parkinson's disease
• MW: 49.8 kDa
• Gene Summary: The vesicular monoamine transporter acts to accumulate cytosolic monoamines into vesicles, using the proton gradient maintained across the vesicular membrane. Its proper function is essential to the correct activity of the monoaminergic systems that have been implicated in several human neuropsychiatric disorders. The transporter is a site of action of important drugs, including reserpine and tetrabenazine (Peter et al., 1993 [PubMed 7905859]). See also SLC18A2 (MIM 193001).[supplied by OMIM, Mar 2008]