TECPR2 (NM_014844) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC221908L4V
- LentiORF®
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Lenti ORF particles, TECPR2 (mGFP-tagged)-Human tectonin beta-propeller repeat containing 2 (TECPR2), transcript variant 1, 200ul, >10^7 TU/mL
Lentiviral Particles: DDK w/ Puro
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USD 365.00
Specifications
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
Tag | mGFP |
Symbol | TECPR2 |
Synonyms | KIAA0329; SPG49 |
Mammalian Cell Selection | Puromycin |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_014844 |
ORF Size | 4233 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC221908).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_014844.3 |
RefSeq Size | 8703 bp |
RefSeq ORF | 4236 bp |
Locus ID | 9895 |
UniProt ID | O15040 |
Cytogenetics | 14q32.31 |
Domains | WD40, TECPR |
MW | 153.8 kDa |
Gene Summary | The protein encoded by this gene is a member of the tectonin beta-propeller repeat-containing (TECPR) family, and contains both TECPR and tryptophan-aspartic acid repeat (WD repeat) domains. This gene has been implicated in autophagy, as reduced expression levels of this gene have been associated with impaired autophagy. Recessive mutations in this gene have been associated with a hereditary form of spastic paraparesis (HSP). HSP is characterized by progressive spasticity and paralysis of the legs. There is also some evidence linking mutations in this gene with birdshot chorioretinopathy (BSCR), which results in inflammation of the choroid and retina. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2015] |
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