UNC5B (NM_170744) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC218267L3V

Lenti ORF particles, UNC5B (Myc-DDK tagged) - Human unc-5 homolog B (C. elegans) (UNC5B), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: UNC5B
• Synonyms: p53RDL1; UNC5H2
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_170744
• ORF Size: 2835 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC218267).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_170744.2, NP_734465.2
• RefSeq Size: 3935 bp
• RefSeq ORF: 2838 bp
• Locus ID: 219699
• UniProt ID: Q8IZJ1
• Cytogenetics: 10q22.1
• Domains: DEATH, tsp_1, ZU5, ig, IGc2, IG
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Axon guidance
• MW: 103.5 kDa
• Gene Summary: This gene encodes a member of the netrin family of receptors. This particular protein mediates the repulsive effect of netrin-1 and is a vascular netrin receptor. This encoded protein is also in a group of proteins called dependence receptors (DpRs) which are involved in pro- and anti-apoptotic processes. Many DpRs are involved in embryogenesis and in cancer progression. Two alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Oct 2011]