Epac2 (RAPGEF4) (NM_001100397) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC217088L3V

Lenti ORF particles, RAPGEF4 (Myc-DDK-tagged)-Human Rap guanine nucleotide exchange factor (GEF) 4 (RAPGEF4), transcript variant 2, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: Epac2
• Synonyms: CAMP-GEFII; CGEF2; EPAC; EPAC 2; EPAC2; Nbla00496
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_001100397
• ORF Size: 2601 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC217088).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001100397.1, NP_001093867.1
• RefSeq Size: 4120 bp
• RefSeq ORF: 2604 bp
• Locus ID: 11069
• UniProt ID: Q8WZA2
• Cytogenetics: 2q31.1
• Protein Pathways: Leukocyte transendothelial migration
• MW: 99.3 kDa
• Gene Summary: Guanine nucleotide exchange factor (GEF) for RAP1A, RAP1B and RAP2A small GTPases that is activated by binding cAMP. Seems not to activate RAB3A. Involved in cAMP-dependent, PKA-independent exocytosis through interaction with RIMS2 (By similarity).[UniProtKB/Swiss-Prot Function]