ERAP2 (NM_022350) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC213608L3V

Lenti ORF particles, ERAP2 (Myc-DDK-tagged)-Human endoplasmic reticulum aminopeptidase 2 (ERAP2), transcript variant 1, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: ERAP2
• Synonyms: L-RAP; LRAP
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_022350
• ORF Size: 2880 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC213608).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_022350.1
• RefSeq Size: 3356 bp
• RefSeq ORF: 2883 bp
• Locus ID: 64167
• UniProt ID: Q6P179
• Cytogenetics: 5q15
• Domains: Peptidase_M1
• Protein Families: Druggable Genome, Protease
• MW: 110.3 kDa
• Gene Summary: This gene encodes a zinc metalloaminopeptidase of the M1 protease family that resides in the endoplasmic reticulum and functions in N-terminal trimming antigenic epitopes for presentation by major histocompatibility complex (MHC) class I molecules. Certain mutations in this gene are associated with the inflammatory arthritis syndrome ankylosing spondylitis and pre-eclampsia. This gene is located adjacent to a closely related aminopeptidase gene on chromosome 5. [provided by RefSeq, Jul 2016]