ADAMTS3 (NM_014243) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC211602L3V

Lenti ORF particles, ADAMTS3 (Myc-DDK-tagged)-Human ADAM metallopeptidase with thrombospondin type 1 motif, 3 (ADAMTS3), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: ADAMTS3
• Synonyms: ADAMTS-4; HKLLS3
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_014243
• ORF Size: 3615 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC211602).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_014243.1, NP_055058.1
• RefSeq Size: 5836 bp
• RefSeq ORF: 3618 bp
• Locus ID: 9508
• UniProt ID: O15072
• Cytogenetics: 4q13.3
• Protein Families: Druggable Genome, Protease, Secreted Protein
• MW: 135.6 kDa
• Gene Summary: This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease, a member of the procollagen aminopropeptidase subfamily of proteins, may play a role in the processing of type II fibrillar collagen in articular cartilage. [provided by RefSeq, Feb 2016]