Scramblase 1 (PLSCR1) (NM_021105) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC207485L2V

Lenti ORF particles, PLSCR1 (mGFP-tagged) - Human phospholipid scramblase 1 (PLSCR1), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: Scramblase 1
• Synonyms: MMTRA1B
• Mammalian Cell Selection: None
• Vector: pLenti-C-mGFP
• ACCN: NM_021105
• ORF Size: 954 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC207485).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_021105.1
• RefSeq Size: 2228 bp
• RefSeq ORF: 957 bp
• Locus ID: 5359
• UniProt ID: O15162
• Cytogenetics: 3q24
• Domains: Scramblase
• Protein Families: Druggable Genome, Stem cell - Pluripotency
• MW: 35 kDa
• Gene Summary: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system.[UniProtKB/Swiss-Prot Function]