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EXDL1 (EXD1) (NM_152596) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC206223L3V
- LentiORF®
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Lenti ORF particles, EXD1 (Myc-DDK tagged) - Human exonuclease 3'-5' domain containing 1 (EXD1), 200ul, >10^7 TU/mL
Lentiviral Particles: mGFP w/ Puro
AAV Particle: DDK
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Specifications
| Product Data | |
| Type | Human Tagged ORF Clone Lentiviral Particle |
| Tag | Myc-DDK |
| Symbol | EXDL1 |
| Synonyms | EXDL1 |
| Mammalian Cell Selection | Puromycin |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_152596 |
| ORF Size | 1542 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC206223).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_152596.2, NP_689809.2 |
| RefSeq Size | 3009 bp |
| RefSeq ORF | 1545 bp |
| Locus ID | 161829 |
| UniProt ID | Q8NHP7 |
| Cytogenetics | 15q15.1 |
| MW | 58.3 kDa |
| Gene Summary | RNA-binding component of the PET complex, a multiprotein complex required for the processing of piRNAs during spermatogenesis. The piRNA metabolic process mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposable elements, preventing their mobilization, which is essential for the germline integrity (By similarity). The PET complex is required during the secondary piRNAs metabolic process for the PIWIL2 slicing-triggered loading of PIWIL4 piRNAs. In the PET complex, EXD1 probably acts as an RNA adapter. EXD1 is an inactive exonuclease (By similarity).[UniProtKB/Swiss-Prot Function] |
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