LMO2 (NM_005574) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC205376L2V
- LentiORF®
Lenti ORF particles, LMO2 (mGFP-tagged) - Human LIM domain only 2 (rhombotin-like 1) (LMO2), transcript variant 1, 200ul, >10^7 TU/mL
Lentiviral Particles: DDK DDK w/ Puro mGFP w/ Puro
AAV Particle: DDK
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Specifications
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
Tag | mGFP |
Symbol | LMO2 |
Synonyms | LMO-2; RBTN2; RBTNL1; RHOM2; TTG2 |
Mammalian Cell Selection | None |
Vector | pLenti-C-mGFP |
ACCN | NM_005574 |
ORF Size | 474 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC205376).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_005574.2 |
RefSeq Size | 2304 bp |
RefSeq ORF | 684 bp |
Locus ID | 4005 |
UniProt ID | P25791 |
Cytogenetics | 11p13 |
Domains | LIM |
Protein Families | Druggable Genome |
MW | 18.2 kDa |
Gene Summary | LMO2 encodes a cysteine-rich, two LIM-domain protein that is required for yolk sac erythropoiesis. The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. The LMO2 transcription start site is located approximately 25 kb downstream from the 11p13 T-cell translocation cluster (11p13 ttc), where a number T-cell acute lymphoblastic leukemia-specific translocations occur. Alternative splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Nov 2008] |
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