EPS8 (NM_004447) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC205300L2V

Lenti ORF particles, EPS8 (mGFP-tagged) - Human epidermal growth factor receptor pathway substrate 8 (EPS8), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: EPS8
• Synonyms: DFNB102
• Mammalian Cell Selection: None
• Vector: pLenti-C-mGFP
• ACCN: NM_004447
• ORF Size: 2466 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC205300).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_004447.4
• RefSeq Size: 4088 bp
• RefSeq ORF: 2469 bp
• Locus ID: 2059
• UniProt ID: Q12929
• Cytogenetics: 12p12.3
• Domains: SH3, PID
• Protein Families: Druggable Genome
• MW: 91.9 kDa
• Gene Summary: This gene encodes a member of the EPS8 family. This protein contains one PH domain and one SH3 domain. It functions as part of the EGFR pathway, though its exact role has not been determined. Highly similar proteins in other organisms are involved in the transduction of signals from Ras to Rac and growth factor-mediated actin remodeling. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]