WFS1 (NM_006005) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC202901L2V
- LentiORF®
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Lenti ORF particles, WFS1 (mGFP-tagged) - Human Wolfram syndrome 1 (wolframin) (WFS1), transcript variant 1, 200ul, >10^7 TU/mL
Lentiviral Particles: DDK DDK w/ Puro mGFP w/ Puro
Product Images
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Specifications
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
Tag | mGFP |
Symbol | WFS1 |
Synonyms | CTRCT41; WFRS; WFS; WFSL |
Mammalian Cell Selection | None |
Vector | pLenti-C-mGFP |
ACCN | NM_006005 |
ORF Size | 2670 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC202901).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_006005.2 |
RefSeq Size | 3640 bp |
RefSeq ORF | 2673 bp |
Locus ID | 7466 |
UniProt ID | O76024 |
Cytogenetics | 4p16.1 |
Protein Families | Druggable Genome, Transmembrane |
MW | 100.3 kDa |
Gene Summary | This gene encodes a transmembrane protein, which is located primarily in the endoplasmic reticulum and ubiquitously expressed with highest levels in brain, pancreas, heart, and insulinoma beta-cell lines. Mutations in this gene are associated with Wolfram syndrome, also called DIDMOAD (Diabetes Insipidus, Diabetes Mellitus, Optic Atrophy, and Deafness), an autosomal recessive disorder. The disease affects the brain and central nervous system. Mutations in this gene can also cause autosomal dominant deafness 6 (DFNA6), also known as DFNA14 or DFNA38. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2009] |
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