WFS1 (NM_006005) Human Untagged Clone
CAT#: SC319529
WFS1 (untagged)-Human Wolfram syndrome 1 (wolframin) (WFS1), transcript variant 1
"NM_006005" in other vectors (6)
Product Images
![](https://cdn.origene.com/img/defaults-img-expression-plasmids.jpg)
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Symbol | WFS1 |
Synonyms | CTRCT41; WFRS; WFS; WFSL |
Vector | pCMV6-AC |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>OriGene sequence for NM_006005.2
CTCCCGTTTGCGCCGCGTTCAGCTGCTCCCGAACAACTTTTCTGCCGGCCCAGAGGCCCC
AGGGCGTCGCAGCGCCGCGTGCGGCCCACTCACGGGCCGGATGGACTCCAACACTGCTCC GCTGGGCCCCTCCTGCCCACAGCCCCCGCCAGCACCGCAGCCCCAGGCGCGTTCCCGACT CAATGCCACAGCCTCGTTGGAGCAGGAGAGGAGCGAAAGGCCCCGAGCACCCGGACCCCA GGCTGGCCCTGGCCCTGGTGTTAGAGACGCAGCGGCCCCCGCTGAACCCCAGGCCCAGCA TACCAGGAGCCGGGAAAGAGCAGACGGCACCGGGCCTACAAAGGGAGACATGGAAATCCC CTTTGAAGAAGTCCTGGAGAGGGCCAAGGCCGGGGACCCCAAGGCACAGACTGAGGTGGG GAAGCACTACCTGCAGTTGGCCGGCGACACGGATGAAGAACTCAACAGCTGCACCGCTGT GGACTGGCTGGTCCTCGCCGCGAAGCAGGGCCGTCGCGAGGCTGTGAAGCTGCTTCGCCG GTGCTTGGCGGACAGAAGAGGCATCACGTCCGAGAACGAACGGGAGGTGAGGCAGCTCTC CTCCGAGACCGACCTGGAGAGGGCCGTGCGCAAGGCAGCCCTGGTCATGTACTGGAAGCT CAACCCCAAGAAGAAGAAGCAGGTGGCCGTGGCGGAGCTGCTGGAGAATGTCGGCCAGGT CAACGAGCACGATGGAGGGGCGCAGCCAGGCCCCGTGCCCAAGTCCCTGCAGAAGCAGAG GCGCATGCTGGAGCGCCTGGTCAGCAGCGAGTCCAAGAACTACATCGCGCTGGATGACTT TGTGGAGATCACTAAGAAGTACGCCAAGGGCGTCATCCCCAGCAGCCTGTTCCTGCAGGA CGACGAAGATGATGACGAGCTGGCGGGGAAGAGCCCTGAGGACCTGCCACTGCGTCTGAA GGTGGTCAAGTACCCCCTGCACGCCATCATGGAGATCAAGGAGTACCTGATTGACATGGC CTCCAGGGCAGGCATGCACTGGCTGTCCACCATCATCCCCACGCACCACATCAACGCGCT CATCTTCTTCTTCATCGTCAGCAACCTCACCATCGACTTCTTCGCCTTCTTCATCCCGCT GGTCATCTTCTACCTGTCCTTCATCTCCATGGTGATCTGCACCCTCAAGGTGTTCCAGGA CAGCAAGGCCTGGGAGAACTTCCGCACCCTCACCGACCTGCTGCTGCGCTTCGAGCCCAA CCTGGATGTGGAGCAGGCCGAGGTCAACTTCGGCTGGAACCACCTGGAGCCCTATGCCCA TTTCCTGCTCTCTGTCTTCTTCGTCATCTTCTCCTTCCCCATCGCCAGCAAGGACTGCAT CCCCTGCTCGGAGCTGGCTGTCATCACCGGCTTCTTTACCGTGACCAGCTACCTGAGCCT GAGCACCCATGCAGAGCCCTACACGCGCAGGGCCCTGGCCACCGAGGTCACCGCCGGCCT GCTATCGCTGCTGCCCTCCATGCCCTTGAATTGGCCCTACCTGAAGGTCCTTGGCCAGAC CTTCATCACCGTGCCTGTCGGCCACCTGGTCGTCCTCAACGTCAGCGTCCCGTGCCTGCT CTATGTCTACCTGCTCTATCTCTTCTTCCGCATGGCACAGCTGAGGAATTTCAAGGGCAC CTACTGCTACCTTGTGCCCTACCTGGTGTGCTTCATGTGGTGTGAGCTCTCCGTGGTCAT CCTGCTGGAGTCCACCGGCCTGGGGCTGCTCCGCGCCTCCATCGGCTACTTCCTCTTCCT CTTTGCCCTCCCCATCCTGGTGGCCGGCCTGGCCCTGGTGGGCGTGCTGCAGTTCGCCCG GTGGTTCACGTCTCTGGAGCTCACCAAGATCGCAGTCACCGTGGCGGTCTGTAGTGTGCC CCTGCTGTTGCGCTGGTGGACCAAGGCCAGCTTCTCTGTGGTGGGGATGGTGAAGTCCCT GACGCGGAGCTCCATGGTCAAGCTCATCCTGGTGTGGCTCACGGCCATCGTGCTGTTCTG CTGGTTCTATGTGTACCGCTCAGAGGGCATGAAGGTCTACAACTCCACACTGACCTGGCA GCAGTATGGTGCGCTGTGCGGGCCACGCGCCTGGAAGGAGACCAACATGGCGCGCACCCA GATCCTCTGCAGCCACCTGGAGGGCCACAGGGTCACGTGGACCGGCCGCTTCAAGTACGT CCGCGTGACTGACATCGACAACAGCGCCGAGTCTGCCATCAACATGCTCCCGTTCTTCAT CGGCGACTGGATGCGCTGCCTCTACGGCGAGGCCTACCCTGCCTGCAGCCCTGGCAACAC CTCCACGGCCGAGGAGGAGCTCTGTCGCCTTAAGCTGCTGGCCAAGCACCCCTGCCACAT CAAGAAGTTCGACCGCTACAAGTTTGAGATTACCGTGGGCATGCCATTCAGCAGCGGCGC TGACGGCTCGCGCAGCCGCGAGGAGGACGACGTCACCAAGGACATCGTGCTGCGGGCCAG CAGCGAGTTCAAGAGCGTGCTGCTCAGCCTGCGCCAGGGCAGCCTCATCGAGTTCAGCAC CATCCTGGAGGGCCGCCTGGGCAGCAAGTGGCCTGTCTTCGAGCTCAAGGCCATCAGCTG CCTCAACTGCATGGCCCAGCTCTCACCCACCAGGCGGCACGTGAAGATCGAGCACGACTG GCGCAGCACCGTGCATGGCGCCGTGAAGTTCGCCTTCGACTTCTTTTTCTTCCCATTCCT GTCGGCGGCCTGAGGATGGTCCGCCACGAGGAGCTTCCAGTGCATGTTGCCATGAGGCCT TTCCCCAGTGTGGCCCCAGCCCGACAGGCATGCACCAGTGCCGCCTGTGCCCACGTGTGC AGACTGTGGCTGCAGAGACCTTGCGACCATGTGTAGATTGCGTGGACCCCGACAAAGGGA AGGCTGCTGCTGAATACCAAGTGTGTTGGGAATTGCATGCCATCTCCACCCTGAGCCTGA CCTTTCTGAGTGACATGGGTGTGCCAGGCTAGACTAGGAGGTTCCGGTGTCTGGAAAAGC ACTTTACAGATGAGATTCCCTCTCCTCCCCCACCTTCAAGCACCCTGTTCCCTCTTTCTT TCTTTTGTGTTGGATTTGTTTAAAAACCAAATAAGCATCTGTGTAACCTCCAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAA |
Restriction Sites | Please inquire |
ACCN | NM_006005 |
OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_006005.2, NP_005996.1 |
RefSeq Size | 3640 bp |
RefSeq ORF | 2673 bp |
Locus ID | 7466 |
UniProt ID | O76024 |
Cytogenetics | 4p16.1 |
Protein Families | Druggable Genome, Transmembrane |
Gene Summary | This gene encodes a transmembrane protein, which is located primarily in the endoplasmic reticulum and ubiquitously expressed with highest levels in brain, pancreas, heart, and insulinoma beta-cell lines. Mutations in this gene are associated with Wolfram syndrome, also called DIDMOAD (Diabetes Insipidus, Diabetes Mellitus, Optic Atrophy, and Deafness), an autosomal recessive disorder. The disease affects the brain and central nervous system. Mutations in this gene can also cause autosomal dominant deafness 6 (DFNA6), also known as DFNA14 or DFNA38. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2009] Transcript Variant: This variant (1) is the longer transcript. Variants 1 and 2 encode the same protein. |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC202901 | WFS1 (Myc-DDK-tagged)-Human Wolfram syndrome 1 (wolframin) (WFS1), transcript variant 1 |
USD 1,222.00 |
|
RC202901L1 | Lenti ORF clone of Human Wolfram syndrome 1 (wolframin) (WFS1), transcript variant 1, Myc-DDK-tagged |
USD 1,522.00 |
|
RC202901L2 | Lenti ORF clone of Human Wolfram syndrome 1 (wolframin) (WFS1), transcript variant 1, mGFP tagged |
USD 1,522.00 |
|
RC202901L3 | Lenti ORF clone of Human Wolfram syndrome 1 (wolframin) (WFS1), transcript variant 1, Myc-DDK-tagged |
USD 1,522.00 |
|
RC202901L4 | Lenti ORF clone of Human Wolfram syndrome 1 (wolframin) (WFS1), transcript variant 1, mGFP tagged |
USD 1,522.00 |
|
RG202901 | WFS1 (tGFP-tagged) - Human Wolfram syndrome 1 (wolframin) (WFS1), transcript variant 1 |
USD 1,422.00 |
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