TBCE (NM_003193) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC201927L4V

Lenti ORF particles, TBCE (mGFP-tagged) - Human tubulin folding cofactor E (TBCE), transcript variant 2, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: TBCE
• Synonyms: HRD; KCS; KCS1; pac2; PEAMO
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: NM_003193
• ORF Size: 1581 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC201927).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_003193.3
• RefSeq Size: 1977 bp
• RefSeq ORF: 1584 bp
• Locus ID: 6905
• UniProt ID: Q15813
• Cytogenetics: 1q42.3
• Domains: CAP_GLY, LRR
• Protein Families: Druggable Genome
• MW: 59.3 kDa
• Gene Summary: Cofactor E is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]