Kcnj10 (NM_001039484) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR227234L1V

Lenti ORF particles, Kcnj10 (Myc-DDK-tagged) - Mouse potassium inwardly-rectifying channel, subfamily J, member 10 (Kcnj10), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Mouse Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: Kcnj10
• Synonyms: BIR10; BIRK-1; Kir1.2; Kir4.1
• Mammalian Cell Selection: None
• Vector: pLenti-C-Myc-DDK
• ACCN: NM_001039484
• ORF Size: 1137 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR227234).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001039484.1, NP_001034573.1
• RefSeq Size: 5407 bp
• RefSeq ORF: 1140 bp
• Locus ID: 16513
• UniProt ID: Q9JM63
• Cytogenetics: 1 79.69 cM
• Gene Summary: May be responsible for potassium buffering action of glial cells in the brain. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium and cesium (By similarity). In the kidney, together with KCNJ16, mediates basolateral K(+) recycling in distal tubules; this process is critical for Na(+) reabsorption at the tubules (By similarity).[UniProtKB/Swiss-Prot Function]