Tnfsf12 (NM_011614) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR224787L4V

Lenti ORF particles, Tnfsf12 (GFP-tagged) - Mouse tumor necrosis factor (ligand) superfamily, member 12 (Tnfsf12), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Mouse Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: Tnfsf12
• Synonyms: Apo3l; Dr3l; Dr3lg; Tweak
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: NM_011614
• ORF Size: 747 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR224787).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_011614.2
• RefSeq Size: 1515 bp
• RefSeq ORF: 750 bp
• Locus ID: 21944
• UniProt ID: O54907
• Cytogenetics: 11 B3
• Gene Summary: Binds to FN14 and possibly also to TNRFSF12/APO3. Weak inducer of apoptosis in some cell types. Mediates NF-kappa-B activation. Promotes angiogenesis and the proliferation of endothelial cells. Also involved in induction of inflammatory cytokines. Promotes IL8 secretion (By similarity).[UniProtKB/Swiss-Prot Function]