Erbin (NM_001005868) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR221851L3V

Lenti ORF particles, Erbb2ip (Myc-DDK-tagged) - Mouse Erbb2 interacting protein (Erbb2ip), transcript variant 1, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Mouse Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: Erbin
• Synonyms: 1700028E05Rik; Erbb2ip; mKIAA1225
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_001005868
• ORF Size: 4353 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR221851).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001005868.1, NP_001005868.1
• RefSeq Size: 6674 bp
• RefSeq ORF: 4353 bp
• Locus ID: 59079
• UniProt ID: Q80TH2
• Cytogenetics: 13 D1
• Gene Summary: Acts as an adapter for the receptor ERBB2, in epithelia. By binding the unphosphorylated ERBB2 'Tyr-1248' receptor, it may contribute to stabilize this unphosphorylated state (By similarity). Inhibits NOD2-dependent NF-kappa-B signaling and proinflammatory cytokine secretion (PubMed:16203728).[UniProtKB/Swiss-Prot Function]