Esrp2 (NM_176838) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR210251L3V

Lenti ORF particles, Esrp2 (Myc-DDK-tagged) - Mouse epithelial splicing regulatory protein 2 (Esrp2), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Mouse Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: Esrp2
• Synonyms: 9530027K23Rik; Rbm35b
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_176838
• ORF Size: 2154 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR210251).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_176838.2, NP_789808.1
• RefSeq Size: 2686 bp
• RefSeq ORF: 2154 bp
• Locus ID: 77411
• UniProt ID: Q8K0G8
• Cytogenetics: 8 D3
• Gene Summary: mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT). Acts by directly binding specific sequences in mRNAs. Binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2 (By similarity).[UniProtKB/Swiss-Prot Function]