Sphk2 (NM_020011) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR209459L3V
- LentiORF®
Lenti ORF particles, Sphk2 (Myc-DDK-tagged) - Mouse sphingosine kinase 2 (Sphk2), transcript variant 2, 200ul, >10^7 TU/mL
Lentiviral Particles: mGFP w/ Puro
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Specifications
Product Data | |
Type | Mouse Tagged ORF Clone Lentiviral Particle |
Tag | Myc-DDK |
Symbol | Sphk2 |
Synonyms | C76851; Sk2; Spk2 |
Mammalian Cell Selection | Puromycin |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_020011 |
ORF Size | 1854 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR209459).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_020011.3 |
RefSeq Size | 3790 bp |
RefSeq ORF | 1854 bp |
Locus ID | 56632 |
UniProt ID | Q9JIA7 |
Cytogenetics | 7 B3 |
Gene Summary | This gene encodes a kinase that phosphorylates sphingosine into sphingosine-1-phosphate, which is involved in cell differentiation, motility, and apoptosis. The encoded protein plays a role in maintaining cellular levels of sphingosine-1-phosphate. The gene product also enhances apoptosis in different cell types and suppresses cellular proliferation. In mast cells, the encoded protein is necessary for influx of calcium, protein kinase C activation, and cytokine production and degranulation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010] |
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